Friday, November 29, 2019

Revolutionary Art

Revolutionary art if a form of modern art through which artists express their personal convictions about certain issues in the society. The pieces of art might also depict political themes (Douglas, 1970). A true revolutionary artist does not care whether the needs of speculative dealers are met or not.Advertising We will write a custom essay sample on Revolutionary Art specifically for you for only $16.05 $11/page Learn More Revolutionary art should not be characterized by sycophancy that is aimed at making collectors like an artist’s work. When an artists is entirely motivated to meet the needs of dealers in their work then the revolutionary attributes in them ceases to exist (Party, 1969). Revolutionary art addresses the living issues of the society without any fear of contradiction. This paper will highlight the purpose of revolutionary art in the society and at the same time discuss how revolutionary art has affected art and artists in Americ a. Many people in the modern society are very reluctant to think about change and therefore revolutionary artsist and other types of revolutionists have a great assignment of ensuring that people’s minds are provoked to start thinking about change (Party, 1969). The society is always faced with inequalities and revolutionary art often seeks to change the status quo (Douglas, 1970). The true purpose of revolution is to fight any kind of injustice in the society through inspiring other people to fight against all evils and forms of injustice in the society. Revolutionary artists use specific themes in their works that actually reflect revolution or the works can help to bring out a new conscience among the people. Revolution art aims to eliminate political struggles and in the process generate political passions. Revolution art has actually changed life and brought liberation in many countries across the world with America being a perfect example. This form of art has completel y changed American art artists in a great way (Porter, 1986). Artists like John Trumbul were very instrumental in American Revolution by making portrait paintings that helped a great deal in helping America gain its independence fro Great Britain. This inspired other artists to explore revolutionary art by focusing on landscape and personal scenes. After the revolutionary war in the late 18th century, American artists stopped using British styles and invented their own unique American styles. All the colonial art styles and architecture were completely phased out in America to indicate revolution (Porter, 1986). These pieces of art helped spread the wave of change even to the most conservative of minds in the wake of independence. This new style of art that emerged after the American revolution helped in bringing a sense of national identity to American citizens and at the same time inspired a new American consciousness.Advertising Looking for essay on art? Let's see if we can help you! Get your first paper with 15% OFF Learn More In conclusion, revolutionary art has become very popular across the world because of the desire for total liberation. Since revolutionary art was invented, people’s perspective about art has completely changed. A piece of revolutionary art should reflect the true revolutionary conviction of the artist without bearing in mind the needs of dealers. Revolutionary art played a key role in bringing change and liberation in countries such as America and in the process becoming very popular. The fundamental role of revolutionary art is to inspire people to fight all forms of evil and injustice in the society. References Douglas, E. (1970). Revolutionary art: A tool for liberation. New York, NY: John Brown Party. Party, B. (1969). Revolutionary art: A tool for liberation. New York, NY: Black Panther Party. Porter, R. (1986). Revolution in history. New York, NY: Cambridge University Press. This essay on Revolutionary Art was written and submitted by user D00msdayMan to help you with your own studies. You are free to use it for research and reference purposes in order to write your own paper; however, you must cite it accordingly. You can donate your paper here.

Monday, November 25, 2019

Benefits from Drinking Milk Essays

Benefits from Drinking Milk Essays Benefits from Drinking Milk Essay Benefits from Drinking Milk Essay This slogan was part of an ad campaign started in 1993 up until February of this year to encourage more and more people to drink cows milk 2. For thousands of years, people have been drinking milk, and its become a sat pale in many of our diets and meals. A. For years weve poured milk into our cereal and poured glasses of milk to accompany our cookies and ores. B. Theres no denying the fact that drinking milk CAN be beneficial for your health , but recent studies have revealed that milk is not as great and healthy as this a d campaign has led people to believe. 3. Im not here to say that all dairy products should be eliminated. Milk, yogurt, a ND cheese can be very healthy when eaten in moderation, but Im here today to t ell you why you may want to cut milk from your diet if you havent already. Body 1. Milk IS nutritious and can be healthy when drunk in moderation. A. A glass of milk contains calcium, protein, Vitamin A, Vitamin D, and many the r nutrients. One of the problems is that a glass of milk also contains pus cells, feces, and n acidic animal protein that increases calcium loss from our bones, but more on that later. Milk also contains bioengineering hormones, antibiotics, and pesticides, all of which are bad for not only us but also the environment. 2. Im sure that some of you here have probably been advised as a child to drink plenty of milk to build strong bones, and to prevent osteoporosis, which is a disease that causes bones to become weak and brittle, in the future. A. A glass of milk has 300 MGM of calcium, which means that its ideal for preventing osteoporosis, right? B. Well according to the Harvard School of Public Health, the answer is no. . Amy Llano PhD, who is the nutrition director for the Physicians Committee f or Responsible Medicine states that the countries with the highest rates of osteoporosis are the ones where people drink the most milk and have the MO SST calcium in their diets. D. The 1 2 year long Harvard Nurses Health Study discovered that those who consumed the most calcium from dairy foods broke more bones than those who rarely drank milk. . According to the American Journal of Epidemiology, consumption of dairy products was associated with an increased risk of hip fracture at an old age. The irony is that the animal protein in milk causes our bodies pH levels to become more acidic, which means that when we ingest milk, calcium is drawn out from our bones to neutralize the effects of this animal protein, and this in turn depl etes the calcium in our bones. In short, the calcium that our bones need to stay strong and healthy is used to cancel out the acidifying effects of milk. 1. Once it leaves the bones, it exits the body through urine, and the net result is a calcium deficit. 3. Research has also shown that milk increases the risk of cancer in men. A. A Harvard study has discovered that men who drank two or more glasses of ilk a day were almost twice as likely to develop prostate cancer as opposed t o those who did not drink milk at all. 4. Cows milk is the perfect drink. If you were a calf. A. Cows milk is perfectly suited for a calf and is capable of turning a pound calf into a pounded cow in just one year. Humans are the only creatures on earth who drink milk past infancy, and the only ones who drink the milk off different creature. i. The truth is that humans arent meant to drink cows milk. 1. 65% of the worlds population is lactose intolerant, and 90% Of East Asian people are lactose intolerant. Milk is generally unhealthy in and of itself . In 2010, research in the Journal of the American Academy of Dermatology has found that there is an association between dairy consumption and acne, and some dermatologists advise their patients to limit their dairy intake 2. Milk is referred to as liquid red meat due to the fact that its very high in saturated fat, which is associated with increased rates of heart attacks. 3. Cow milk has three times more protein than human milk, which creates disturbances in our metabolisms. A. These disturbances have detrimental consequences to the health of our bones. There are many better, healthier ways to obtain the nutrients that milk offers without the downsides. 1. Milk substitutes include almond, soy, rice, coconut and hemp milks, which can be obtained at most supermarkets. . Yogurt is healthy to eat and is much healthier than milk and you wont have to deal with any of these adverse consequences. 3. You can get plenty of calcium and nutrients from vegetables and nuts, and you wont get the gastrointestinal problems that come with drinking too much milk. Conclusion 1. All in all, while milk does have its benefits, the disadvantages outweigh the advantages. Adjust does not make any sense to continue drinking milk when there are man other healthier alternatives.

Thursday, November 21, 2019

Comparing Coca-Cola Enterprise and Pepsi Co. Financial Management Research Paper

Comparing Coca-Cola Enterprise and Pepsi Co. Financial Management - Research Paper Example They are equally important for all, Management, Owners and prospective Investors. The first thing that attracts investors to a Company is its profitability and what the investors will get in return of their investment, as profit whether distributed or not is Profitability measures are important to company managers and owners alike. If an entity has to attract investors , the owners have to show some attractive profits to lure them into investing and for that the profitability ratios are the key. Company’s overall efficiency and performance is shown by the profitability ratios and one can easily compare financial information available for two or three companies to ensure the worth of each after making and investment. Financial Ratios used to determine the satisfaction of a Company’s Stockholders: The Return on Equity is an important ratio as it calculates the company’s earnings performance and tells the shareholders how much are they getting on every $1 of their investment (as capital) made in the company. This ratio explains the shareholders how effectively their money is being employed and getting the profits for the company each period. Shareholders, on comparing the ratios with similar companies or industry as a whole, can get the satisfaction or dissatisfaction that their monies are utilized properly and getting the desired results or not. However, it should be kept in mind while making the comparisons that there are variations in this ratio among some types of businesses. The Dividend Payout Ratio, as the shareholders are always looking for the return, not in form of figures in the financial statements but also in their hands as ready cash. This ratio indicates the dividend a company pays to its common shareholders on every $1 net profit it earns. That is how muc h of the profit is distributed by the company to its shareholders as return and how much is retained. And no matter how forward looking the shareholders are they are always looking for some materialistic return and dividend is one of those things that satisfy the shareholders the most. Guidelines to invest in one of those companies: The debt ratio gives an idea how much the Company is indebted as compared to the assets it held. That is the amount of total liability per $1 of its total assets. The more the debts are the more riskier is the company and its operations to invest in as its shows that the company is not able to pay its debts from the assets it holds if all the amount is called currently. Further it also indicates that in case of liquidation the shareholders equity would be utilized and the owners share in the assets will be reduced or nullified. Comparing Coca-Cola Enterprise and Pepsi Co, in this regard Coca-Cola Enterprise is less risky because of its 0.946 debt ratio a s compared to Pepsi Co’s 0.562. The Current Ratio highlights the liquidity of the company, higher the current ratio means more liquid the company is and that the company’

Wednesday, November 20, 2019

Nucleic acid hybridisation and Nucleic acid probes Essay

Nucleic acid hybridisation and Nucleic acid probes - Essay Example For instance, if a DNA strand with a desired nucleotide sequence is to be detected from a mixture of many other strands, an oligonucleotide containing a few complementary bases to the desired sequence can be prepared and attached to an anchor such as a membrane or a paper. When soaked in a solution having a mixture of many strands, the one, which is complementary to the oligonucleotide, will bind to it through complementary base pairing, also known as â€Å"zippering† (Lodish et al, 2004, p. 11). When double stranded DNA is heated in a dilute salt solution, its two strands separate because of the breakdown of complementary base pairing (melting). This strand separation is called denaturation. The temperature at which the two complementary strands separate is called the melting temperature ‘Tm’, and is affected by the percentage of G.C base pairs, ion concentration of the solution, presence of destabilising compounds like urea, and the pH of the solution (Lodish et al, 2004, p. 105). A particular fragment of DNA or RNA whose nucleotide sequence is complementary to a gene or nucleotide of interest is called a nucleic acid probe. A nucleic acid probe has to be designed in such a way that it hybridises through complementary base pairing to the target DNA or RNA that has to be detected. It should be long enough (about 20 nucleotide long) to pair exclusively to the target nucleotide sequence. Probes are labeled with radioactive tracers, histochemical compounds or fluorescent dyes to enable their detection from a heterogeneous mixture of nucleic acids (Nussbaum et al, 2004, p.41). For instance, 32P labeled probes are developed using polynucleotide kinase that transfers a

Monday, November 18, 2019

Amazon's Kindle Fire Aspects of Consumer Behavior Research Paper

Amazon's Kindle Fire Aspects of Consumer Behavior - Research Paper Example In this paper, we shall elaborate on these aspects and how they affect the marketing of Amazon’s Kindle products. The very first aspect that those marketing the Kindle product should consider is the fact that the product should be built or created to be more efficient than those of rival companies. This is essential for the marketing of the product because consumers tend to consider efficiency when buying a product. Consumers may prefer to go buy a product which is fast and wastes less time when they are using it even if the product is more expensive than similar products from other companies. The company should work on improving the speed of products if it intends to attract more consumers by promoting the efficiency of its products. Another aspect of marketing which should consider consumer behavior is the frequent changing of how the product is packaged. Consumers tend to believe that the products with a look that is new and different from the previous one is better. Amazon should therefore ensure that the look of its Kindle products is changed frequently to ensure that consumers are kept interested in them. New tools should be incorporated into the new forms of the product to make its use easier and this can be made a basis upon which the product is promoted (Poole, 2011). Consumers tend to prefer portable products which they can use anywhere at their own convenience. The Kindle products should be made more portable than they already are so that its marketers can use it as a strategy for marketing the product. Consumers are more likely to want to buy a portable product because of the ability to use them in any situation. They can read an eBook anywhere at any time and this can be used as a marketing strategy when promoting this product. The best marketing strategy which considers consumer behavior is the promotion of the product as being cheaper than those of rival products. The company should ensure that the prices of its products are lower than

Saturday, November 16, 2019

Accuracy of Rectal Water Contrast Transvaginal Ultrasound

Accuracy of Rectal Water Contrast Transvaginal Ultrasound Abstract Objectives:  To compare the accuracy of rectal water contrast transvaginal ultrasound (RWC-TVS) and double-contrast barium enema (DCBE) in assessing the presence and extent of bowel endometriosis. Methods:  This prospective study included 198 patients of reproductive age with suspicion of bowel endometriosis. RWC-TVS and DCBE were performed before operative laparoscopy by two groups of physicians specialized in endometriosis, each blinded to the results of the other groups. Findings of RWC-TVS and DCBE were compared with histological results. The severity of pain experienced during RWC-TVS and DCBE was measured by a 10 cm visual analog scale. Results:  In total, 110 of the 198 women had bowel endometriosis nodules confirmed at laparoscopy and histopathology patients. For the diagnosis of bowel endometriosis DCBE and RWC-TVS had a sensitivity of 96.4% and 88.2%, specificity of 100% and 97.3%, positive predictive value of 100% and 98.0%, negative predictive value of 98.0% and 88.0% and accuracy of 98.0% and 92.4% respectively. DCBE was associated with more intense pain than was RWC-TVS. Conclusions: RWC-TVS and DCBE have similar accuracy in the diagnosis of bowel endometriosis, but patients tolerate RWC-TVS better than they do DCBE. Keywords: double-contrast barium enema; rectal water contrast transvaginal ultrasound; bowel endometriosis; diagnosis Introduction Bowel endometriosis affects between 4-37% of patients with endometriosis1. Intestinal endometriosis lesions may have variable size2. Small endometriosis nodules located on the serosal surface of the bowel rarely cause symptoms and, therefore, do not require treatment2. Larger endometriosis nodules infiltrate the bowel wall and may cause various gastrointestinal complaints such as dyschezia, diarrhea, constipation, abdominal bloating and intestinal cramping1, 3. These symptoms may mimic irritable bowel syndrome. Symptoms caused by bowel endometriosis are nonspecific, often resulting in misdiagnosis or delay in diagnosis4. Physical examination may suggest the presence of rectovaginal endometriosis; however, it has poor accuracy in diagnosing rectosigmoid nodules5, 6. Until recently, the ultrasonic diagnosis of endometriosis was limited to patients with ovarian endometriomas and other imaging techniques were used for the assessment of bowel endometriosis including rectal endoscopic ultrasound, transvaginal ultrasound (TVS), double-contrast barium enema (DCBE), magnetic resonance imaging (MRI), multidetector computerized tomography enema (MDCT-e) and virtual colonoscopy7-10. TVS is a reliable non-invasive method to assess the presence and the extent of bowel endometriosis11. Injecting saline through a catheter into the rectum during TVS (rectal-water contrast TVS, RWC-TVS) may facilitate the identification of rectosigmoid nodules, the assessment of the depth of infiltration of endometriosis in the intestinal wall and estimation of the degree of stenosis of the bowel lumen. However, no previous study compared the accuracy of DCBE and RWC-TVS in the diagnosis of rectosigmoid endometriosis4, 12, 13. A preoperative diagnosis of the presence and extent of bowel endometriosis is necessary to determine whether surgery is required and to plan the surgical procedure with the colorectal surgeon14. Knowing before surgery the size and number of intestinal endometriosis nodules, the depth of infiltration of the nodules in the intestinal wall and the degree of stenosis of the bowel lumen allows determining whether surgery is required and may allow the surgeons to choose between nodulectomy and bowel segmental resection15, 16. In addition, determining before surgery the extent of bowel endometriosis allows the surgeon to inform the patient about the potential benefits and complications of the surgical procedure that will be performed. In fact, postoperative complications and evolution of digestive symptoms after surgery may differ between patients undergoing nodulectomy and those undergoing segmental resection, with a higher incidence of bladder-voiding dysfunction and postoperative constipation in patients undergoing the latter procedure. In this study, we compared the accuracy of DCBE and RWC-TVS in assessing the presence and extent of bowel endometriosis. Methods Study population This prospective study was performed between May 2012 and Aug 2016. Participants were recruited among patients of reproductive age scheduled for laparoscopy with strong suspicion of intestinal endometriosis based on symptoms and clinical examination. During this period, the imaging workup required that both DCBE and RWC-TVS were performed in patients with suspicion of bowel endometriosis. Institutional review board approval was obtained before initiating the study. Patients participating in the study signed a written consent form. Inclusion criteria for the study were: reproductive age and suspicion of deep pelvic endometriosis; presence of gastrointestinal symptoms that might be caused by bowel endometriosis; and desire to undergo complete surgical excision of the endometriosis. Patients were excluded from the study if they had previous bilateral ovariectomy; previous barium radiological examination or radiological diagnosis of bowel endometriosis; previous colorectal surgery; previ ous episodes suggestive of intolerance to iodinated contrast medium; renal or hepatic failure; refusal to undergo DCBE and psychiatric disorders. Symptoms were systematically investigated during the study period and they were recorded in a database. The presence of dysmenorrheal, deep dyspareunia, non-menstrual pelvic pain and dyschezia was investigated and the intensity of their symptoms was assessed in all patients on a 10 cm visual analog scale (VAS), on which the left extremity represented absence of pain and the right extremity indicated maximum intensity of pain. The presence of the following gastrointestinal symptoms was assessed: diarrhea-predominant irritable bowel syndrome; constipation-predominant irritable bowel syndrome; passage of mucus in the stools; rectal bleeding; intestinal cramping; and abdominal bloating. A symptom analogue scale questionnaire was used to estimate the severity of each gastrointestinal symptom. DCBE and RWC-TVS results were compared with surgical and pathologic findings. The radiologists performing DCBE and the gynecologists performing TVS were each blinded to the others results. They were blinded to the clinical data and knew only that the presence of intestinal endometriosis was suspected. All patients underwent laparoscopy within 1 month from the completion of the diagnostic investigations. Intestinal endometriosis was defined as the disease infiltrating at least the muscularis propria. Endometriosis foci located on the bowel serosa were considered peritoneal and not bowel endometriosis. The present study determined the accuracy of DCBE and RWC-TVS in assessing the presence of bowel endometriosis, estimating the size and the number of bowel endometriosis nodules and determining the presence of peritoneal endometriosis infiltrating only the intestinal serosa. Rectal water contrast transvaginal ultrasound technique Two physicians performed all the examinations according to a standardized procedure. RWC-TVS was performed by using a Voluson E6 machine connected to a transvaginal transducer. After the transducer had been introduced into the vagina, an assistant inserted a 6-mm flexible catheter through the anus into the rectal lumen up to a 15 cm distance from the anus. A gel infused with lidocaine was used to facilitate passage of the catheter. A 50 mL syringe was connected to the catheter and warm sterile saline solution was injected inside the rectum and the sigmoid under ultrasonic control. The amount of saline solution needed to show the rectosigmoid ranged between 100 and 350 mL, depending on the distensibility of the intestinal wall. One hundred milliliters of saline solution were continuously and slowly infused at the beginning of the procedure; the rest of the solution was infused when requested by the ultrasound. During ultrasound, when saline solution was not being infused, backflow through the catheter was prevented by placing a Klemmer forceps on the catheter. There w as no significant leakage of saline solution into the space between the catheter and the anus. Images were obtained before, during and after saline injection. Bowel endometriosis appears ultrasonographically as a nodular, solid, hypoechoic lesion, adjacent to and/or penetrating the intestinal wall. Hyperechoic foci may sometimes be present within the lesion. Intestinal distension allows defining the limits of the intestinal nodules and in particular the various layers of the rectal wall in order to estimate the depth of infiltration. The intestinal serosa is hyperechoic; the two layers of the muscularis propria appear as hypoechoic strips separated by a fine hyperechoic line; the submucosa is hyperechoic; the muscularis mucosa is hypoechoic and the interface between the lumen and the mucosal layer is hyperechoic. Rectal endometriosis infiltration is demonstrated by the fact that the hypoechoic nodule penetrates the intestinal wall and, in general, it thickens the muscularis mucosa. Two different ultrasonic signs are commonly used to describe this condition. Double-contrast barium enema All DCBE procedures were carried out using a motorized tilting table for fluoroscopic and radiological examination. In preparation, patients maintained a low-residue diet for 1 day prior to the examination in order to keep the enteric content fluid. The examination was performed after intramuscular administration of 20 mg (1 ampoule) Scopolamine in order to induce colonic hypotonia. The presence of bowel endometriosis was diagnosed on DCBE when the bowel lumen was narrowed at any level from the sigmoid to the anus in association with crenulation of the mucosa and/or speculation of contour. Tolerability of the examinations Immediately after each examination patients were asked to rate the discomfort encountered during DCBE and RWC-TVS by means of a 10 cm visual analogue scale (VAS), mild pain was defined as a VAS score of 5. Surgery and histological evaluation The surgeons examined the reports and the images of DCBE and RWC-TVS prior to laparoscopy. Although the diagnosis of recto-sigmoid endometriosis and its treatment were based on laparoscopic findings. All surgical procedures were performed laparoscope by a team of gynecological and colorectal surgeons with extensive experience in the treatment of pelvic and bowel endometriosis. In all cases, after adequate adhesiolysis, the sigmoid colon and rectum were systematically examined to verify the presence of endometriosis lesions. Bowel endometriosis lesions were removed by intestinal resection in cases of a single lesion >3 cm in diameter, a single lesion infiltrating at least 50% of the circumference of the intestinal wall or three or more lesions infiltrating the muscular layer. In all other cases of bowel endometriosis partial- or full-thickness disk resection was performed. Intestinal lesions infiltrating only the serosal layer of the bowel wall were excised by shaving. All visible les ions suspected to be endometriosis were excised and sent for histological examination in agreement with our clinical protocol. The surgical specimens were evaluated by histological; the depth of infiltration of the endometriosis nodules in the bowel wall was assessed. In cases of nodulectomy the specimens were macroscopically oriented along the intestinal wall (from the serosa towards the mucosa) and cut into macro sections of 2 mm thickness. From each macrosection tissue blocks of 1.5 cm length were obtained in variable numbers according to the size of the lesion, and from each tissue block a 5  µm section was obtained for microscopically evaluation. In cases of bowel resection the specimen was opened longitudinally through its entire length and 2mm longitudinal bands of bowel wall, reaching the two resection margins and passing through all macroscopically visible lesions, were cut. These bands were sampled in tissue blocks and 5  µm sections were obtained for microscopic evaluation. Statistical analysis Sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) were calculated for both DCBE and RWC-TVS. The diagnostic value of each test was also assessed using positive likelihood ratio (LR+) and negative likelihood ratio (LR-). Efficacy parameters were calculated with 95% confidence intervals (CIs). McNemars test with the Yates continuity correction was used to compare the accuracy of DCBE and RWC-TVS in the diagnosis of intestinal endometriosis. McNemars test was used to compare the number of patients in which the number of rectosigmoid nodules was correctly identified by DCBE and RWC-TVS. The accuracy of the measurement of nodule size by imaging techniques was estimated by subtracting the size of the nodule as measured by the techniques from the size of the nodules measured at histology. The nonparametric Mann-Whitney test was used to compare the intensity of pain experienced by patients during DCBE and RWC-TVS, the chi-square test was used to co mpare the type of pain (mild, moderate or severe) and Spearmans rank correlation coefficient was used to determine whether there was a correlation between the intensity of pain experienced by patients during the two techniques. Data were analyzed using the SPSS software. p Results Study population A total of 198 patients were enrolled in the study and all underwent surgery were included in this study (Figure 1). The main demographic characteristics of the study are demonstrated in Table 1. The intensity of pain and gastrointestinal symptoms are presented in Table 2. Surgery and histology demonstrated that 110 patients (55.6%) had bowel endometriosis nodules. The endometriosis lesions infiltrating the intestinal serosa in 28 patients. The remaining 82 patients had only pelvic endometriosis with no evidence of intestinal lesions. The largest intestinal endometriosis nodule was found locate on the sigmoid colon in 53 patients, on the rectum in 30 patients, at the rectosigmoid junction in 20 patients, on the ileum in 5 patients and on the caecum in 2 patients. The endometriosis lesions infiltrating only the intestinal serosa were located on the sigmoid colon in 15 cases, on the rectum in 5cases and at the rectosigmoid junction in 3 cases. The mean ( ±SD) length of the resected bowel segment was 12.2  ± 3.6 cm. The diagnosis of endometriosis was confirmed in all the excised nodules by histological exam. Furthermore, it demonstrated that the deepest endometriosis nodule infiltrated the muscularis propria in 62 patients (56.4 %), the submucosa in 3 1 patients (28.2%) and the mucosa in 17 patients (15.5%). Accuracy of RWC-TVS and DCBE in the diagnosis of bowel endometriosis The accuracy, sensitivity, specificity, PPV, NPV, LR+ and LR- of DCBE and RWC-TVS in the diagnosis of bowel endometriosis are described in Table 3. DCBE identified 106 of 110 patients with bowel endometriosis (96.4%). In 4 patients endometriosis nodules infiltrating the muscularis propria of the rectum were not identified, which were excised by partial-thickness nodulectomy. RWC-TVS identified 97 of 110 patients with intestinal endometriosis (88.2%). RWC-TVS did not identify 4 ileal lesions, 2 cecal lesions, 4 sigmoid nodules and 3 rectal nodules infiltrating the muscularis propria. Furthermore, we identified 4 of these patients had large bilateral endometriosis ovarian cysts, which may have hampered the identification of intestinal nodules. There was 2 false positive on RWC-TVS-a rectovaginal endometriosis nodule that was judged to infiltrate the muscularis of the rectum. Surgery confirmed the presence of the rectovaginal nodule but did not reveal infiltration of the rectal muscularis. The sensitivity, specificity, PPV, NPV, LR+, LR- and accuracy of the two techniques in the diagnosis of intestinal endometriosis were shown in Table 3. McNemars test showed that there was no significant difference in the accuracy of the two techniques in the diagnosis of bowel endometriosis (P=0.109). Histology examination demonstrated that endometriosis infiltrated the submucosa or mucosa of the rectosigmoid colon in 53 patients. DCBE correctly identified the depth of infiltration in 27 of these patients (50.9%), while RWC-TVS correctly identified the depth of infiltration in 20 of them (37.7%) (P=0.126). All the other nodules that were seen to infiltrate the submucosa or mucosa at histology were judged to reach only the muscularis at DCBE and RWC-TVS. Both techniques had no cases of false-positive diagnosis of submucosal or mucosal infiltration. Both DCBE and RWC-TVS underestimated the size of the endometriosis nodules; however, the underestimation was greater for RWC-TVS than for DCBE (Table 4). In addition, in both imaging techniques the underestimation was greater for nodules with diameter≠¥30 mm. Tolerability of DCBE and RWC-TVS DCBE was safely performed in all the patients. During both the examinations all patients tolerated intestinal distension and in no patient was it necessary to interrupt the procedure. However, the intensity of pain experienced during DCBE was significantly higher than the intensity of pain experienced during RWC-TVS (Table 5). A positive correlation was observed between the intensity of pain experienced by the patients during the two examinations (Spearman correlation coefficient=0.575; p Discussion To the best of our knowledge, this is the first study demonstrated that DCBE and RWC-TVS have similar accuracy in the diagnosis of bowel endometriosis. Both RWC-TVS and DCBE underestimated the size of bowel endometriosis nodules, but under estimation was greater for RWC-TVS than for DCBE, particularly when the nodules had largest diameter ≠¥ 30 mm (Table 4). The choice of the ultrasonic technique is often based on the experience of the ultrasonographers rather than on evidence of superiority of one technique compared to the others. In fact, TVS must be performed by highly skilled, it has been recently estimated that the learning curve for an accurate diagnosis of deep pelvic endometriosis by TVS requires performing about 40 cases17. Therefore, it may be difficult to achieve such experience for ultrasonographers working in small hospital. The main advantage of DCBE could be that, with a retrograde distension of the entire colon, this technique may provide a complete overview of t he whole colon18. In the current study, the distension was targeted to the rectosigmoid because the aim of the study was the comparison with RWC-TVS and endometriosis lesions of the right colon are beyond the field of view of a transvaginal approach. Furthermore, we did not compare the accuracy of RWC-TVS with TVS alone, which was the objective of a previous study. RWC-TVS was chosen for the comparison with DCBE because of the personal experience of the authors and of the common criterion of bowel distension with fluid. The usefulness of this technique was subsequently confirmed by the same authors in larger series. Furthermore, other authors confirmed that intestinal distension and opacification using ultrasound gel helps to visualize rectosigmoid endometriosis nodules19, 20. Previous studies have suggested that TVS could reliably diagnose rectosigmoid endometriosis. The sensitivity of TVS for detecting rectosigmoid endometriosis is between 91 and 98%, the specificity between 97 and 100%, the PPV between 97 and 100% and the NPV between 87 and 98%21-24. Recently, RWC-TVS has been developed to facilitate identification of intestinal lesions in patients with rectovaginal endometriosis and to determine the depth of infiltration of endometriosis in the intestinal wall25. TVS has been extensively used in patients with bowel endometriosis; while only little data is available on the use of DCBE in these patients. This study demonstrated that DCBE and RWC-TVS have similar accuracy in the diagnosis of bowel endometriosis. Both techniques precisely estimated the length of the rectosigmoid nodules, but DCBE was more precise than RWC-TVS in assessing the distance between the endometriosis nodule and the anal verge9. Obviously, the extensive experience of the radiologi st and the gynecologist in DCBE and RWCTVS, respectively, may have influenced the accuracy of these techniques in diagnosing bowel endometriosis24, 26. The findings may be explained by the fact that when performing imaging techniques, particularly RWC-TVS, it might be difficult to choose the plane in which the irregular endometriosis nodule has the largest diameter. However, the difference between the estimated size of the nodule and the largest diameter as measured on histopathology was quite small and, in most cases, it seems unlikely that this difference would affect the choice of nodulectomy or bowel resection as treatment27. Importantly, patients tolerated RWC-TVS better than they did DCBE. These findings are in line with those of previous studies demonstrating the accuracy of TVS in the diagnosis of bowel endometriosis and comparing TVS with other techniques such as MRI and rectal endoscopic ultrasound11, 28-30. The potential benefits of introducing aqueous contrast medium into the rectum during TVS have been questioned. TVS is an operator-dependent procedure and it is possible that the differences observed in the accuracy of this technique are determined by the experience of the ultrasonographer carrying out the procedure31. However, adding intestinal aqueous contrast to TVS may facilitate the identification of rectosigmoid lesions. Other techniques have been proposed for improving the accuracy of TVS in the detection of deep endometriosis, such as sonovaginography or the use of large quantities of ultrasound transmission gel (12 mL) in the probe cover32. Up to now, no study has established whether any one of these ultrasonic techniques is superior to the others in the diagnosis of deep endometriosis. TVS should be considered the first-line investigation in patients with deep endometriosis, and allows the diagnosis of intestinal lesions24. Other investigations such as RWC-TVS, MDCT-e, MRI, rectal endoscopic ultrasound and DCBE may be used to determine the characteristics of intestinal endometriosis, such as the size and number of nodules, the depth of infiltration of the nodules in the intestinal wall and the degree of stenosis of the bowel lumen33-35. RWC-TVS has several advantages over the other techniques. It is less expensive than MDCT-e and MRI and the equipment required to perform the procedure is commonly available to gynecologists, who are usually involved in the management of patients with endometriosis. A recent study has shown that RWC-TVS allows estimation of the degree of stenosis of the intestinal lumen caused by endometriosis36. Unfortunately, this parameter was not examined in the current study- the major limitation of our investigation. Theoretically, RWC-TVS may also allow determination of the extent of the disease along the longitudinal intestinal axis. Obviously, RWC-TVS cannot determine the presence of intestinal nodules located proximally to the sigmoid because these lesions are beyond the field of TVS. This study had several limitations. First, the experience of the ultrasonographer in RWC-TVS may influence the accuracy of these techniques in diagnosing bowel endometriosis. Second, the surgeons were aware of the findings of DCBE and RWC-TVS. Although in an ideal prospective study the surgeons should be blinded to the findings of the preoperative investigations, this theoretical study design appears unethical in clinical practice because diagnostic imaging may facilitate the identification of intestinal endometriosis nodules during surgery. Furthermore, the knowledge of the findings of the preoperative investigations may only help the surgeons in identifying endometriosis nodules that were actually present. Third, RWC-TVS and DCBE did not estimate the percentage of the circumference of the intestinal wall infiltrated by endometriosis, a criterion used to choose between nodulectomy and bowel resection. Therefore, patients scheduled for nodulectomy on the basis of DCBE and RWC-TVS fin dings should be informed that bowel resection might be required for the complete excision of intestinal endometriosis. Future studies should examine whether DCBE and RWC-TVS can reliably estimate what percentage of intestinal circumference is infiltrated by endometriosis. DCBE may still have a role in the diagnostic workup of patients with suspected bowel endometriosis. When TVS or RWC-TVS demonstrates large intestinal nodules infiltrating the bowel muscularis, bowel resection can probably be performed without further investigation unless the surgeon wants to exclude intestinal lesions located proximally to the sigmoid. In contrast, when ultrasound demonstrates a single bowel nodule that may be excised by nodulectomy, DCBE should be used to exclude the presence of other intestinal nodules and, thus, to adequately plan the surgical procedure with the colorectal surgeon and the patient. Conclusions This study showed that RWC-TVS is a reliable technique for determining the presence and extent of bowel endometriosis and that it has an accuracy similar to that of DCBE. However, RWC-TVS may sometimes underestimate the presence of multiple bowel nodules and can be performed easily in an ambulatory setting and it is better tolerated by patients. It may be hypothesized to combine TVS and DCBE to achieve a complete preoperative assessment of the bowel in order to offer to the patients an adequate counseling and the most appropriate one-step surgical treatment.

Wednesday, November 13, 2019

Essay --

In Africa there have been many wars and problems with poverty as well as famine that lead to war. One specific war was the civil war in Congo also known as The Great War of Africa. The war in Congo lasted from August 1998 to July 2003 and left thousands of people dead or injured. The war started because of issues in the DRC which stands for the Democratic Republic of Congo. The war was a long and terrifying war that ended when the transitional government of Democratic Republic of Congo took power. Africas unfriendliness has continued with the Lords Resistance Army Insurgencies and The Kivu as well as Ituri conflicts. The civil war in congo has made a huge impact on the people of africa and how they live today. The Kivu conflict was an armed conflict against the FARDC ,which stands for The Military of the Democratic Republic of the Congo, and the Hutu power group Democratic forces for the liberation of Rwanda in 2004. The main group against the FARDC was the rebel tutsi forces under the command of Laurant Nkunda. As a result of this conflict the CNDP, which stand for the National Congress Defence of the People, divided R0wandan Hutu power in 2009. The Ituri was a conflict between the Agriculturalist Lendu and Pastoralist Hema ethnic groups of the Ituri region which is in the northeastern region of the DRC. This started as early as 1972 and the most recent conflict was in 1999 to 2003 but has had small amounts of conflict until 2007. The lendu ethnicity was represented by the FNI which stands for Nationalist and integrationist Front. The hema ethnicity was represented by the UPC which stands for the Union of Congolese Patriots. there was a lot of violence like large massacres that both ethn icity did. The BBC found out that from 199... ... to blend into the forest and wait for them to attack; the nature of the army even further undermines the military operations. There are many attempted solutions that the security council of UN tried, but did not completely succeed in stopping the war. In the future there will not be as much fighting. There will be less conflict and more peace with the government and the FDLR. Hopefully in the future the people of Africa will not live in poverty as well as famine and have more money than what they have now. They could have enough money to survive longer and to buy medicine as well as food. In africa there should be more laws passed to for gun control and the government should try to get bigger and stronger to stop the FDLR. The UN should try to do more to stop the war in Africa. there are many solutions that that were tried but failed in stopping the war in Africa.

Monday, November 11, 2019

Music and Crime

Music and crime are two very distinctly different but related things. Music has effects other than providing pleasure to listeners. On one hand, music may affect emotions in such a way that it may trigger a person to justify a criminal act. On the other hand, it can also help suppress a potential criminal’s emotions, which may possibly prevent crime from happening. For most people, classical music is that which usually has a positive effect. It may calm the violent instinct that is deep within a person, especially those who have no other means to release these instincts.   Thus, classical music may have a negative effect on crime. Music and crime can be correlated through an individual’s mood. The mood that music inherently suggests is usually reflected in one's thoughts. To clarify, crime may be usually driven by a person's mentality, while music can influence one's thinking.   In some forms of music, there are seemingly subliminal messages that may cause a variety of effects for different personalities. The subliminal messages that could influence a person can be a contributing factor in crimes (Cooper). However, other forms of music, like classical music, are popularly believed to have positive effect that can prevent potential criminals from committing crimes. For instance, some studies also show that classical music has the effect of keeping the violent instinct down.   This can be attributed to the kind of slow, meditative and soothing quality that classical music has in trying to deal with certain elements, such as brute force and violence. It can bring back gentle and tender memories of a person, which would most likely result in bringing out the gentle emotions that a person might have hidden deep inside of him (Partenheimer).This can have the unexpected effect of eliminating the kind of violent instinct that leads to crime.   For instance, in West Palm Beach, Florida, authorities found that playing classical music in the streets have lessened the criminal incidents in the said street (USA Today). Everyone is subjected to music with embedded messages.   There are kinds of music that seems harmless and innocent that may actually influence one to commit crimes if it has an embedded negative message.   This occurs because people have different levels of comprehension; these negative messages may unconsciously encourage them to commit crimes. If a person was exposed to music with a positive message, like that of classical music, the person that might have been previously inclined to commit crimes will be persuaded to gently stop committing crimes.   Moreover, a person's mood can also be influenced by music.   Basically, it works in the same way subliminal messages do. However, it only targets more of the emotional side of a person (Wilson). People who might have been in the mood for violent acts or criminally prosecutable actions will be very reluctant to engage in these kinds of acts if there is a big emotional weight pressing their feelings. This is the power that classical music has; it is capable of influencing the kind of mood that a person has. Classical music may help encourage resistance for criminal thoughts that will prove to be beneficial to one's psychological state. Classical music has the kind of ephemeral quality that the human mind cannot possibly comprehend in all its subtleties.   For this reason, the mind cannot actively stop the kind of influence that music exerts. The human mind unconsciously follows the lead made by the kind of music it is exposed to since the sounds are not hindered by simple syntax of human language. The kind of wordless but emotionally tangible quality that is inherent in classical music takes it straight to the inner workings of the human emotion. There is nothing but the defenseless inner self or ego that bears to receive the kind of message that the music has.   Since classical music transcends the usual human emotional barriers through its capability to affect emotions, the person's thoughts and mood is usually affected as well.   In turn, it also strongly influences the actions of the person. Classical music is powerful because it targets the basic emotions that can influence a person’s intention to commit crimes. In addition, classical music can influence a person in a relatively peaceful or positive way.   Even if there are various reasons behind criminal or deviant acts coming in many forms, all of them are at least connected to some emotions as part of the underlying reasons hidden deep in the part of the human psyche. Classical music, which has an unfathomable effect on the human psyche, can highly influence a person’s decision to commit a crime. In conclusion, classical music is conducive to positive emotions; therefore, it has a negative effect on crime because it triggers a positive effect on one's emotions and thinking.   The effect of such musical forms and the mood it represents has the capacity to diminish a person's violent instinct, as well as to keep criminal thought at bay.   In this way, classical music can be instrumental in preventing crimes. Works Cited â€Å"Classical Music on West Palm Corner Deters Crime.†Ã‚   USA Today. 8 July 2001. The Associated Press. 22 March 2008   Cooper, Candy. â€Å"Subliminal Messages, Heavy Metal Music and Teen-age Suicide.† San Francisco Examiner. 29 September 1989. 5 March 2008 â€Å"What are subliminal effects?† World of Mouth Experiment. 2007. 5 March 2008 Wilson, Stephanie. â€Å"The effects of Music on Perceived Atmosphere and Purchase Notions in Restaurant.†(Abstract). Psychology of Music 31.1 (2003): 93-112. 5 March 2008 Partenheimer, David. â€Å"Violent Music Lyrics Increase Agreesive Thoughts and Feelings, According to New Study.† APA. 2003. 5 March 2008 â€Å"Classical Music on West Palm Corner Deters Crime.†Ã‚   USA Today. 8 July 2001. The Associated Press. 22 March 2008 < http://www.usatoday.com/news/nation/2001/07/08/music.htm>      

Friday, November 8, 2019

Pharoah Tutanchamen essays

Pharoah Tutanchamen essays Tutanchamen name means living image of AMEN. Tutanchamen birth name was Tutankhaten. He was the son of Pharaoh Amenophis IV and his Queen, Kiya. He married his half sister Ankheseenamun, the daughter of Amenophis IV and Queen Neferrtiti. He became king when he was 9 years old (around 1333BC). Imagine ruling an entire country when you are only nine! King Tut ruled Egypt, which is located in the northeast corner of Africa along the banks of the Nile. Tutankhamen became king after the death on Ikhnaton in 1362 BC. During most of his rule he lived in Memphis, near present day Cairo. Egypt was actually governed by his senior officials and Ay, senior minister of state. Peace was brought to Egypt during his reign as the worship of Amon, which was abandoned under Ikhnaton, was restored and Thebes the city sacred to Amon, Egyptians enjoyed life on earth and they planned for life in the here after. They lived in impressive houses and enjoyed dressing up and wearing wigs. Most people wore clothes made of linen. They were entertained by musicians while feasting on goose, meat, figs, dates and pomegranates and they drank grape or date wine. Some of their favorite pets were monkeys, King Tuts reign was very short He died suddenly during the war with the Hittite people. He was only 19 years old. He had no heirs. No one knows the mystery of his death. He was buried in the Valley of the Tombs, of the kings of southern Egypt. The Egyptians believed that life after death was similar to life on earth. They protected and preserved themselves for the next life. The pyramids protected the bodies and mummification preserved the body. The mummification process could take as long as 70 days. All the organs were removed and put in jars to dry. Then the body was embalmed and treated with oils and molten resin. The body w ...

Wednesday, November 6, 2019

The Great Compromise essays

The Great Compromise essays In May 1787, fifty-five delegates from eleven of the thirteen American states assembled in Philadelphia. Their goal was to revise the current government created by the Articles of Confederation, which had been in effect since 1781. The Articles had created a weak alliance among the states. The national government had no way to levy taxes or regulate commerce. The delegates who were in attendance at the Philadelphia convention had come in general agreement that there were defects in the Articles of Confederation that should be remedied. But instead of convening and deciding to list and remedy the defects of the Articles, the delegates at the convention took another course of action. Soon after George Washington was elected to be the presiding officer of the meeting, the Virginia delegation, relying heavily on the draftsmanship of James Madison, presented a new plan for an entirely new national government. This plan became the main topic of debate at the convention for the next several weeks. When the delegates decided to make the Virginia Plan the focus of their agenda, they had essentially changed the task for which they had been sent to Philadelphia. The defects of the Articles took a backseat to the more pressing issue of how to design a true national government. The Virginia Plan called for a strong union of the states into a centralized national government. Under the plan, the national government would be divided into three governing branches the legislative, the executive, and the judicial. The legislative branch would consist of two houses. The first house would be directly chosen by the people, and the second house would be chosen by the first house from candidates nominated by state legislatures. The executive and the national judiciary would be chosen by the national legislature. The executive along with some members of the judiciary would be selected to serve on a council of revision, which...

Monday, November 4, 2019

Substance abuse Essay Example | Topics and Well Written Essays - 2000 words

Substance abuse - Essay Example There are many ongoing debates in regards to this issue, and this is especially so in particular regards to that of the exact distinction between substance abuse and substance dependence; these are two totally separate issues however they are often confused or considered wrongly as being the same thing. In regards to be able to show a proper example of substance abuse, we will be discussing one movie in particular, 28 days. By thoroughly examining this movie and understanding about the environment, the characters, the situations take place, and all of the related issues in this regards we will be able to come to a much more critical and knowledgeable viewpoint in regards to what substance abuse actually is and what can be done about it. There are many critical issues that will be discussed using this film, and this is what will be dissertated in the following. 28 Days is a movie in which basically what happens is a big-city newspaper columnist is forced to enter a drug and alcohol rehabilitation center after stealing a limousine and crashing it into a house; the main character is Gwen Cummings who is played by Sandra Bullock, who is a Caucasian woman that ends up getting into a car crash on the day of her sister’s wedding, and she is then given a choice between either going to prison or going to a rehab center, and so she ends up choosing the rehab center. However, she is not exactly willing to admit that she has a problem with alcohol, and so at the beginning of the rehab center program she is quite negative and is extremely resistant in regards to taking part in any of the treatment programs that they have to offer. However, after a certain point she starts to realize that she does in fact have a problem, and that rather than simply using alcohol she does in fact have an addiction, and she then gradually begins to re-examine her life and she becomes willing to at least give it a try and get herself help and get better.

Saturday, November 2, 2019

Written communication assessment ( 30%) Essay Example | Topics and Well Written Essays - 2000 words

Written communication assessment ( 30%) - Essay Example PSA is considered to be the leading supporter of pharmacists’ rights. It helps influence the attitudes and policies of the government and society through networking, continuing education, coordination, and health promotion activities. The Consumers Health Forum (CHF) speaks in behalf of the health consumers. It is an independent non-governmental organization which helps fashion Australia’s health care system by encouraging the consumers to participate in establishing health policies. The CHF gathers data, opinions, and complaints from the people and brings them to the attention of concerned government officials. Through their actions, government officials can make the necessary adjustments in policies for the good of the public. According to CHF, the general public should be given affordable, safe and quality medicines and health services. They also believe that consumers should have a chance to be involved in the management of their health care. Consumers should also be given access to vital health information in ways they can easily understand. The CHF prioritizes the safety and quality of health care services especially for patients with chronic conditions. The organization members come from different c ommunity and health sectors, including illness-based groups, population groups and other health-interest groups. (â€Å"Our CHF – Who are we?†). Through these various members, they give a voice to the consumer public. In 1928, the Pharmacy Guild of Australia was established. It successfully bonded together a number of pharmacy organizations from various States. It is registered as an employees’ organization and it has about 4500 member pharmacists throughout Australia. The Guild functions as a single entity, not a federation. The Guild involves itself in several areas of health care such as health